A small research study conducted by the Department of Health’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) found that Synthroid is the first synthetic levothyroxine synthetic analog to be found in the U. S. market. The study was funded by the NIH and is being supported by the Office of Dietary Health and Prevention at the Food and Drug Administration.
The researchers compared Synthroid to levothyroxine tablets, and found that Synthroid was similar to levothyroxine tablets, but the two were different. The researchers also found that Synthroid was more stable than levothyroxine tablets.
The researchers also found that levothyroxine tablets were more effective at stabilizing thyroid hormones, while Synthroid was not.
The study authors write:
“Synthroid is a very simple, bioequivalent medication that has been used in the treatment of hypothyroidism for over 10 years. The primary advantage of this medication is its long-lasting potency, which can last up to 10 years and provides a reasonable option for patients with mild to moderate hypothyroidism. The medication is also relatively inexpensive, providing patients with a cost-effective option for managing their hypothyroid symptoms.”
“It is important to note that Synthroid is not a substitute for T3 or T4, but rather a synthetic analog of T3 and T4. This makes it more palatable for patients with hypothyroidism, and it is also more expensive to obtain. Synthroid is available as generic medications in the U. and can be obtained at a lower cost than T3 and T4, but its efficacy in hypothyroidism is still not fully understood.”
References:1. The NIDDK Drug Safety Communication: Synthroid and Levothyroxine
Janssen Health, Inc. (2011) Synthroid and Levothyroxine: Safety and Toxicity. Available at:
2. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).3. National Heart, Lung and Blood Institute (NHLBI).
4.5. The ClinicalTrials.gov website:.
6.7. The NIDDK ClinicalTrials.gov website:.8. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).9.10.11.12.13.14.15.16.17.18.19.20.21.22.23.24.
25.26.27.28.29.30.31.32.33.Thyroid disorders, also known as "Hashimoto's thyroiditis," are a common and potentially irreversible condition that can lead to significant fatigue and other symptoms. Thyroid hormones play a crucial role in the body's energy production and overall cellular function. While they are necessary for normal cellular function, they can also play a role in the development of various autoimmune diseases, particularly in individuals with Hashimoto's thyroiditis.
Thyroid hormones are produced naturally in the thyroid gland. The thyroid gland's hormones are produced primarily in the adrenal gland. Thyroid hormones are secreted from the adrenal glands by glands such as the thyroid, stomach, gall bladder, ovary, testes, uterus, and thyroid gland. Synthroid is a synthetic form of the thyroid hormone triiodothyronine (T3), which is a potent energy-producing hormone. It is used in thyroid cancer management, autoimmune diseases, and autoimmune disorders.
The use of levothyroxine is one of the first treatments for thyroid disorders in Hashimoto's thyroiditis. It is available in both branded and generic forms. Brand-name levothyroxine is often preferred over generics due to its lower cost and the availability of more affordable generic medications. While it is important to follow your doctor's instructions when starting treatment with levothyroxine, it is still important to be aware of potential side effects and ensure that you are taking the right medication for your individual needs.
Levothyroxine is not recommended for individuals under the age of 18 years if they have Hashimoto's thyroiditis, as it can cause serious hypothyroidism, a condition characterized by symptoms such as fatigue, weight gain, and muscle weakness. For these individuals, thyroid hormone replacement therapy (TRT) should be started as soon as possible after the symptoms begin to subside. It is important to continue taking levothyroxine even if the symptoms improve or do not improve after a few days of treatment.
Levothyroxine may cause side effects such as nausea, headache, breast tenderness, and weight changes. If you experience any of these symptoms while taking levothyroxine, stop taking levothyroxine and contact your doctor immediately.
Levothyroxine is excreted in breast milk. Levothyroxine is usually used in combination with breast-feeding while taking TRT. It is not recommended to use levothyroxine alone for long-term thyroid hormone replacement therapy due to possible serious hypothyroidism (see section 4).
Levothyroxine should not be used during pregnancy unless it is clearly necessary. It is also not recommended to breastfeed while taking levothyroxine due to potential harm to the fetus.
It is not recommended to breastfeed while taking levothyroxine due to potential harm to the infant.
Levothyroxine passes into breast milk. It is not recommended to take it during pregnancy unless clearly necessary. It should not be used by children below the age of 18 years unless it is clearly necessary. It is not recommended to breastfeed while taking levothyroxine as it may affect the nursing baby and cause harm to the nursing infant.
Levothyroxine is used in adults and children aged 6 years and older in combination with levothyroxine therapy to manage hypothyroidism. It is not recommended to use it in children below the age of 6 years unless clearly necessary. It should not be used by individuals of all ages.
Levothyroxine is not approved for use in children under 6 years of age. It is not recommended to take levothyroxine by mouth or in dairy products or antacids unless clearly necessary.
Levothyroxine is not recommended for use by women or individuals over the age of 18 years. It is not recommended to use levothyroxine by mouth or in dairy products or antacids unless clearly necessary.
Levothyroxine is available in tablet form and should be taken by mouth with or without food. It is important to take levothyroxine at the same time each day to maintain stable thyroid hormone levels and to avoid side effects. It is not recommended to take levothyroxine more often than once a day without talking with your doctor. Your doctor will monitor your symptoms for any changes in your symptoms while taking levothyroxine.
Levothyroxine can cause side effects such as nausea, headache, breast tenderness, and weight changes. If you experience any of these symptoms while taking levothyroxine contact your doctor immediately.
Levothyroxine should not be used by individuals who are allergic to levothyroxine, unless it is clearly necessary.
Interactions between drugs that may cause a problem may be:
This makes it difficult to determine the cause of your condition. If you have any questions about your medication, check with your doctor or pharmacist.
The information contained herein is not a substitute for the medical advice of your own. It contains a guide for the reader to:
Keep all prescription and over-the-counter medication in the original container, with the lid tightly closed. Store at room temperature. Do not freeze. Store away from reach.
In case of overdose, get medical help or contact a Poison Control Center right away.
Symptoms of an overdose may include:
If you develop any of these symptoms while taking Synthroid, stop taking it immediately and contact your doctor. If your condition improves or worsens, contact your doctor.
Symptoms of an allergic reaction may include:
If you are about to receive a medication from someone else, be advised to consult with your doctor before taking it. There may be an increased risk of developing a dangerous drug interaction when using these medications. Discuss your treatment options with your doctor.
In case of overdose, you should contact your doctor or nearest hospital immediately.
In case of overdose, you should contact your doctor or nearest hospital.
I'm a 35 year old female who was diagnosed with hypothyroidism. My primary care physician has told me that I am under a year old, and I'm a lot of things. I have been on a gluten-free diet, and I was told that I'm no longer able to have children. I had a thyroid test that came back positive, but I'm still not sure if it's correct.
I have a family history of thyroid disease and it's been very frustrating. I'm currently taking (brand name) Synthroid. I'm now taking a generic form of levothyroxine, which I take in a different dosage as well. The test came back positive, and I'm wondering if I should have a generic brand. I know I can always switch brands if I want, but I don't want to have to go through this again with a different dosage because of the side effects, so I'm going to stick with the generic and hope that I don't have to switch brands again.
I'm currently taking Synthroid and the brand names are brand name. I have read that brand name levothyroxine is a lot more expensive than generic (it's generic, I believe), but I'm not sure if this is true. I'm also currently using brand name Synthroid and the brand names are brand name Synthroid and Nature-Throid. I don't want to switch brands again, and if I do want to change brands, I'm more than willing to do so.
I'm currently on the generic version of Synthroid. I know I need to take the generic version, but I'm also hoping that I will switch brands again. I'm hoping that I can find a way to take brand name Synthroid again.
I don't know if the generic is right for me. I have read that generic levothyroxine is the best way to take thyroid hormone. I'm also currently taking brand name levothyroxine. I have read that this is a generic option, but I'm not sure why I'm being given brand name levothyroxine. I'm confused. Any other alternatives would be fine, but I'm not sure if I want to take brand name Synthroid again. I'm also unsure about switching brands, and if I need to change brands again, I'm a bit worried about the cost. Any other thoughts would be most appreciated!
Thanks in advance for any input, I'm trying to figure out if this is the best option for me. I am on brand name levothyroxine, and it's the only brand I know of that is a lot more affordable than Synthroid. I know it isn't the most cost-effective, but I'm still a bit nervous about the brand name.
Thank you in advance for the info. I have read that brand name levothyroxine is a lot more expensive than generic, but I don't know if it's the same for me. I'm looking for some information about generic levothyroxine.
This is the generic name, and it's the only brand name I know of that is a lot more affordable than Synthroid.
I understand this is a generic, but I have been on generic levothyroxine for the past 2 weeks and my symptoms are gone. I don't know if this is the same generic. The generic is just as good as the brand name, but I am not sure if it's the same for me.
I am on Synthroid, and I take it for my hypothyroidism. The only difference is my thyroid test came back positive, and I am wondering if this is the same as the generic.
I am wondering if there is something I can try to switch brands of, but I'm a bit unsure about switching brands.
Thanks for the detailed info! I'll see what I can do.
EDIT:Hi,
I know it's hard to explain the exact details, but here goes: Synthroid is not a "generic" product. It's a brand-name medication that is usually manufactured by the same company. It is not a thyroid medication, it's a thyroid hormone replacement therapy that is used to treat hypothyroidism, but it is a synthetic form of the thyroid hormone T3. Both Synthroid and levothyroxine contain the same active ingredient called T4, but are chemically different. The brand name Synthroid is the generic, while levothyroxine is the brand name. In fact, Synthroid is the brand name for the generic.
From June 2019 through June 2023, the manufacturer of Synthroid has received offers for over-the-counter Synthroid and Synthroid alternatives. These manufacturers offer Synthroid brand-name or generic alternatives to the brand-name version of the drug. The manufacturer may also provide coupons and other information related to the Synthroid and Synthroid alternatives.
For Synthroid, this manufacturer offers a $25 coupon to eligible patients for up to a month’s supply. This coupon provides an opportunity for patients to save money on their prescriptions and can help cover out-of-pocket costs for patients who are uninsured or under-insured. The manufacturer also offers free shipping for Synthroid or Synthroid alternatives, which may reduce the cost of the medication in the long run.
For Synthroid, this manufacturer offers a $35 coupon to eligible patients for up to a month’s supply.
If you or a loved one is eligible to purchase Synthroid or Synthroid alternatives from this manufacturer, please visit our Patient Assistance Program to receive your FREE Synthroid and Synthroid Alternatives coupon. If you are eligible, your Synthroid and Synthroid alternatives will be shipped directly to you.
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